Article Title:

Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomized controlled trial

(Click the name of the journal article to download the full text pdf)

Author:

Jeffrey A. Morgan, MD

Publication
Issue Date:

Lancet
October 14, 2006

Moderator:

Jonathan C. Trent, MD, PhD
Assistant Professor of Medicine
Sarcoma Medical Oncology
The University of Texas
M.D. Anderson Cancer Center
Houston, Texas

Learning Objectives:

After taking part in this activity, participants should be able to:

• Compare the clinical benefit and tolerability with sunitinib compared with placebo in patients with advanced gastrointestinal stromal tumors (GISTs) after failure and discontinuation of imatinib
• Discuss the clinical implications of the study's findings
• Evaluate existing clinical trial data relating to the treatment with sunitinib in patients with unresectable imatinib-resistant GISTs
  
  

Faculty Disclosures:

Jeffrey A. Morgan, MD, reports no such relationships to disclose.

Jonathan C, Trent, MD, PhD, reports no such relationships.

The NCME staff reports no financial relationships to disclose.